Typically, no.
If they can take it further, they will. If they can't due to other issues, it won't stop them wanting to or one of the 2 pining over the other.
I'm sure it happens from time to time but a genuinely platonic relationship between 2 likeminded people of the opposite sex? Not the sort of thing I'd place a bet on.
Mod me? You don't even know me!