Homestuck
Penny Arcade
Cyanide and Happiness
8-bit Theater
I honestly heavily considered Lore Olympus going in, because I wanted a more serious pick for my Rushmore, and I do think Webtoons deseeve to be in the conversation at least. It would probably be my fifth pick. And I guess Homestuck kind of fits that niche.
I also almost said "fuck it" and picked Cucumber Quest because I enjoyed it back in the day.