I coasted through from my late 20's through early 40's, partying like a rockstar and abusing myself. Body didn't seem to 'betray' me, at least not in a gradual sense. I just kind of abruptly hit a wall where I felt like garbage all the time, and the hangovers started lasting more than a day.
Dialed things back. Started eating better and working out. I currently feel better than I did in my 20's.