Autosave does not activate very often, so I recommend saving often, just in case you game over.
Quick Travel exists, but it takes a while to get it. When you do get it, you have to be standing in one of the Quick Travel spots to activate it and you activate it on the map.
If you fail a white check, you can try again if you level up the associated stat. You can also try again under special circumstances, usually something that would give you a bonus to rolling (like learning something new).
I can't live forever
With my head and my heart in the clouds