Afterbirth was the poor one. Repentence was great. It does take some getting used to the changes. Probably the biggest one is that angel deals are superior to devil deals. Plus there are some items that were worthless and received some nice buffs. Biggest example off the top of my head is Holy Water.
Irony posted... It's like fucking $60
That's for everything. Rebirth plus the 3 DLCs.