i never watched trigun in its entirety, so i don't have a solid opinion of it yet. outlaw star has a cool setting and stuff, but yeah, it kind of doesn't go anywhere towards the end iirc.
hm...baccano?
my favorite anime is probably clannad and clannad after story, but those are romantic comedy/slice of life.
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XS2 is the only good Xenosaga game - Lady Ashe
http://backloggery.com/cwistofu