SHODAN, make Shepard really jittery and unable to bring his customs.
BD Joe, throw Wesker in a Taxi
Zero, destroy your body to harm X and destroy his armor. Put your soul into the XD-Dragoon
Yuri, fuse the XD-Dragoon and Diablo.
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I'm too tired to drive anywhere, anyway, right now, do you care if I praise Black Turtle?
Call me numbers.