Well, I guess maybe the controls if you don't play a lot of PC games. But you can just plug in a controller and play it.
Other than that there is no difference between the versions that I know of.
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http://28.media.tumblr.com/tumblr_lcb35gGx0t1qailr4o1_500.gif
http://www.megavideo.com/?v=57N0YAEJ