From: mnkboy907 | #009
It used to be 100 (that number I don't really get, other than being a nice round number), but with ratings declining more and more over the years, less shows are making it to five seasons.
If you do stripped syndication (run it Monday-->Friday), you can go 20 weeks with 100 episodes before having a rerun. That's almost five months.
Of course, why 20 weeks is more special than 19 or 21 I couldn't tell you.
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