PC? Console?
Don't know if it freezes a bunch on PC like it does on consoles(which is usually hit or miss for some people), but that's also another good reason to manually save every once in a while. Plus you may run into a stupid glitch where you can't move side to side or something(can't exactly recall what I couldn't do), and it becomes really annoying, but was fixed by picking a lock. Happened late in the game(which made it 10x worse), and my last manual save was so long ago.
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