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Topic	Coronavirus Topic 14: Forced to Finish the Fight: The Finale: Final Mix Vol. 2
Forceful_Dragon 11/29/21 1:38:42 PM #233:	What is this medicine? TROMETHAMINE makes blood and urine more alkaline or less acidic. It is used to treat metabolic acidosis, a condition where the body produces too much acid or when the kidneys are not removing enough acid from the body. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Tham Source: https://my.clevelandclinic.org/health/drugs/19820-tromethamine-solution-for-injection The effects on cardiac resuscitability of iso-osmolal solutions of tris-hydroxymethyl-aminomethane (tromethamine), sodium bicarbonate (NaHCO3) and sodium chloride placebo were compared in 30 domestic pigs using a well-established model of electrically induced cardiac arrest and resuscitation. We hypothesized that a carbon dioxide (CO2) consuming buffer like tromethamine would reduce and sodium bicarbonate would increase the respiratory acidosis of mixed venous blood, which had recently been demonstrated in our laboratory, Tromethamine did decrease and sodium bicarbonate did increase both arterial and mixed venous CO2 during cardiopulmonary resuscitation (CPR). Both concentrations of end-tidal CO2 and coronary venous PCO2 were significantly lower after tromethamine than after bicarbonate. However, tromethamine produced an unexpected vasodilator effect with reduction of mean aortic and coronary perfusion pressures to levels that are known to reduce resuscitability and survival independently of its buffer action. Neither resuscitability nor survival was altered by bicarbonate therapy in comparison with sodium chloride placebo. Source: https://pubmed.ncbi.nlm.nih.gov/2851015/ So the first article is about the drugs purpose which is to affect acidity in blood/urine. No mention of hearts. The second is a study done to determine if that effect could prove useful in cases of saving someone in cardiac arrest. It did not. Neither information is from a "fact checker". These are simply the facts themselves. It is demonstrably false to call it a heart attack medication. --- ~C~ FD https://imgur.com/dGDfxaw <cite>Forceful_Dragon posted [p:960460309] in Coronaviru... [t:79585719]...</cite> <quote><quote>What is this medicine? TROMETHAMINE makes blood and urine more alkaline or less acidic. It is used to treat metabolic acidosis, a condition where the body produces too much acid or when the kidneys are not removing enough acid from the body. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Tham</quote> Source: https://my.clevelandclinic.org/health/drugs/19820-tromethamine-solution-for-injection <quote>The effects on cardiac resuscitability of iso-osmolal solutions of tris-hydroxymethyl-aminomethane (tromethamine), sodium bicarbonate (NaHCO3) and sodium chloride placebo were compared in 30 domestic pigs using a well-established model of electrically induced cardiac arrest and resuscitation. We hypothesized that a carbon dioxide (CO2) consuming buffer like tromethamine would reduce and sodium bicarbonate would increase the respiratory acidosis of mixed venous blood, which had recently been demonstrated in our laboratory, Tromethamine did decrease and sodium bicarbonate did increase both arterial and mixed venous CO2 during cardiopulmonary resuscitation (CPR). Both concentrations of end-tidal CO2 and coronary venous PCO2 were significantly lower after tromethamine than after bicarbonate. However, tromethamine produced an unexpected vasodilator effect with reduction of mean aortic and coronary perfusion pressures to levels that are known to reduce resuscitability and survival independently of its buffer action. Neither resuscitability nor survival was altered by bicarbonate therapy in comparison with sodium chloride placebo.</quote> Source: https://pubmed.ncbi.nlm.nih.gov/2851015/ So the first article is about the drugs purpose which is to affect acidity in blood/urine. No mention of hearts. The second is a study done to determine if that effect could prove useful in cases of saving someone in cardiac arrest. It did not. Neither information is from a "fact checker". These are simply the facts themselves. It is demonstrably false to call it a heart attack medication. --- ~C~ FD https://imgur.com/dGDfxaw</quote> ... Copied to Clipboard!
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