Current Events > New Study Finds Unintended Consequences of CRISPR Gene Editing

(+) Yeah! (+)

https://gizmodo.com/new-study-finds-unintended-consequences-of-crispr-gene-1827692218


We speculate that current assessments may have missed a substantial proportion of potential genotypes generated by on-target Cas9 cutting and repair, some of which may have potential pathogenic consequences following somatic editing of large populations of mitotically active cells, the authors of the study from the Wellcome Sanger Institute in the United Kingdom write in the paper published this week in Nature Biotechnology. Basically, past research may have missed lots of CRISPRs potentially harmful consequences.
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Well, yeah.
If your added or removed base pairs don't end up to an exact multiple of three, you've fucked up the entire DNA strand after that point.

Or, if didn't seal your splice properly, you could easily create a ring chromosome by accident.

Questionmarktarius posted...

Well, yeah.
If your added or removed base pairs don't end up to an exact multiple of three, you've fucked up the entire DNA strand after that point.

Or, if didn't seal your splice properly, you could easily create a ring chromosome by accident.

f r a m e s h i f t m u t a t i o n
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We kept asking for crispier chips, but then we dug too deep and found the Balrog
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Coffeebeanz posted...

We kept asking for crispier chips, but then we dug too deep and found the Balrog

I honestly thought CRISPR was some as seen on TV thing for cooking that people buy then never use since I started noticing the word lately

HI, BILLY MAYS HERE TO TELL YOU ABOUT THE CRISPR FRYER
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they took our genes.
broke our DNA
killed our mouse.
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bump
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Playing god has unforeseen consequences? Ya don't say.
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EternalDivide posted...

Playing god has unforeseen consequences? Ya don't say.

we're all the playthings of god. he loves us but also likes to torment us sometimes.
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So in other words, minus the scary headline, they're uncovering flaws in the process that they need to correct before the technique is ready for human usage.

Cool. This is how science works.
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Someone is going to end up creating a viral pathogen.
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I'm trying to be optimistic about this leading to cures for auto-immune diseases, but realistically I don't think that I'll live long enough to be cured.
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Coffeebeanz posted...

We kept asking for crispier chips, but then we dug too deep and found the Balrog

lmao
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So NOW they tell me nature isn't perfect.
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ClunkerSlim posted...

@The23rdMagus posted...

So in other words, minus the scary headline, they're uncovering flaws in the process that they need to correct before the technique is ready for human usage.

Cool. This is how science works.

Um, but humans are already using it. Didn't you see that John Oliver episode where the random guy at home is playing around with this thing and injecting himself?

That random guy needs too, if he seriously thinks that's a good idea.

ElatedVenusaur posted...

ClunkerSlim posted...

@The23rdMagus posted...

So in other words, minus the scary headline, they're uncovering flaws in the process that they need to correct before the technique is ready for human usage.

Cool. This is how science works.

Um, but humans are already using it. Didn't you see that John Oliver episode where the random guy at home is playing around with this thing and injecting himself?

That random guy needs too, if he seriously thinks that's a good idea.

It's not as big a deal as you think. The worst part is you just feel real itchy after. Tasty though. Itchy. Tasty.
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iPhone_7 posted...

Someone is going to end up creating a viral pathogen.

Pretty sure this is how the Resident Evil backstory starts
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The23rdMagus posted...

So in other words, minus the scary headline, they're uncovering flaws in the process that they need to correct before the technique is ready for human usage.

Cool. This is how science works.

This holy shit

Bad headline is bad
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