Current Events > Literally a pig heart in a human and no topic for it.

(+) Yeah! (+)

smdh

https://www.reuters.com/markets/commodities/us-man-recovering-after-breakthrough-pig-heart-transplant-2022-01-10/

U.S. man recovering after 'breakthrough' pig-heart transplant

"CHICAGO, Jan 10 (Reuters) - A U.S. man with terminal heart disease was implanted with a genetically modified pig heart in a first-of-its-kind surgery, and three days later the patient is doing well, his doctors reported on Monday.
The surgery, performed by a team at the University of Maryland Medicine, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools.

If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.
This was a breakthrough surgery and brings us one step closer to solving the organ shortage crisis. There are simply not enough donor human hearts available to meet the long list of potential recipients, Dr. Bartley Griffith, who surgically transplanted the pig heart into the patient, said in a statement.

We are proceeding cautiously, but we are also optimistic that this first-in-the-world surgery will provide an important new option for patients in the future, Griffith added.

For 57-year-old David Bennett of Maryland, the heart transplant was his last option.

"It was either die or do this transplant. I want to live. I know its a shot in the dark, but its my last choice, Bennett said a day before his surgery, according to a statement released by the university.

To move ahead with the experimental surgery, the university obtained an emergency authorization from the U.S. Food and Drug Administration on New Year's Eve through its compassionate use program.

"The FDA used our data and data on the experimental pig to authorize the transplant in an end-stage heart disease patient who had no other treatment options, said Dr. Muhammad Mohiuddin, who heads the University's program on xenotransplantation - transplanting animal organs into humans.

About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to organdonor.gov.

Bennett's genetically modified pig heart was provided by Revivicor, a regenerative medicine company based in Blacksburg, Virginia. On the morning of the surgery, the transplant team removed the pig's heart and placed it into a special device to preserve its function until the surgery.

Pigs have long been a tantalizing source of potential transplants because their organs are so similar to humans. A hog heart at the time of slaughter, for example, is about the size of an adult human heart.

Other organs from pigs being researched for transplantation into humans include kidneys, liver and lungs.

Prior efforts at pig-to-human transplants have failed because of genetic differences that caused organ rejection or viruses that posed an infection risk.
Scientists have tackled that problem by editing away potentially harmful genes.

In the heart implanted in Bennett, three genes previously linked with organ rejection were "knocked out" of the donor pig, and six human genes linked with immune acceptance were inserted into the pig genome.

Researchers also deleted a pig gene to prevent excessive growth of the pig heart tissue.

The work was funded in part with a $15.7 million research grant to evaluate Revivicor's genetically-modified pig hearts in baboon studies.
In addition to the genetic changes to the pig heart, Bennett received an experimental anti-rejection drug made by Kiniksa Pharmaceuticals based in Lexington, Mass."

I did it before it was cool

Piggoons

This makes me very uneasy, but I'm very happy for him and hope he lives a long and healthy life

1 step closer to manbearpig

https://gamefaqs.gamespot.com/a/user_image/8/8/1/AANZVmAACy7R.jpg

I'm thinkin of keeping one in the freezer just in case.

vacuum sealed of course

BuckVanHammer posted...

I'm thinkin of keeping one in the freezer just in case.

vacuum sealed of course

A pig heart or a human?

imagine laying on a table about to be knocked out knowing youre the first person to ever receive a heart from another animal

thats gotta be terrifying, like certain death terrifying

Irony posted...

A pig heart or a human?

pig. I got plenty of human already

Is he expected to survive more than a few days or is this a completele shot in the dark, one in a thousand chance of survival?

The Bionic Porkchop.

Cocytus posted...

smdh

shaking my dick head?

DeadBankerDream posted...

Is he expected to survive more than a few days or is this a completele shot in the dark, one in a thousand chance of survival?

The heart is genetically modified, but this is a first so it's unknown.

I wonder if it comes with increased durability or something

the patient woke up with a healthy appetite for rocks

Reminds me of South Park

https://youtube.com/watch?v=El3TIsfpTbE

VigorouslySwish posted...

imagine laying on a table about to be knocked out knowing youre the first person to ever receive a heart from another animal

thats gotta be terrifying, like certain death terrifying

I agree, to the point where I don't like thinking too much about it. But he knew he was at death's door otherwise, and this was his last chance.

Kramer was right

Chimera

Dorfmann_ posted...

Kramer was right

https://youtu.be/-X0Hcnuro-Q

Eh bring on the pig warriors I say.

A life saved is a life saved.

https://en.m.wikipedia.org/wiki/Pig_Heart_Boy