Current Events > What is your opinion on Ozempic / Wegovy?

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Dark_Arbron
02/22/24 9:53:29 PM
#51:


[LFAQs-redacted-quote]


Same with my mother.

Its telling that the first post didnt even need to qualify that it meant Ozempic being used for weight loss rather than its actual purpose and everyone knew what TC was getting at anyway. Its a problem that doctors prescribe it to people who dont need it.


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NightingaleMD
02/23/24 12:22:11 PM
#52:


[LFAQs-redacted-quote]



Hopefully you mean type 2 or his doctor is committing malpractice.

This is from Semaglutide/Ozempic's official indication:

Use: Labeled Indications
Diabetes mellitus, type 2, treatment (Ozempic, Rybelsus): As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus; risk reduction of major cardiovascular events (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke) in adults with type 2 diabetes mellitus and established cardiovascular disease (Ozempic only).
Weight management, chronic (Wegovy): As an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial BMI of 30 kg/m2 (obesity), or 27 kg/m2 (overweight) in the presence of at least one weight-related comorbid condition (eg, hypertension, type 2 diabetes mellitus, dyslipidemia) and pediatric patients 12 years of age with an initial BMI at the 95th percentile standardized for age and sex (obesity).

And separately, as a contraindication:

- Diabetes mellitus: Do not use in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis; not a substitute for insulin.

This is all very intuitive if you know the medicine well. Type 2 works with this medicine because this increases insulin sensitivity in people that are insulin-resistant.

It cannot be used for type 1 diabetics because Type 1 is an insulin deficiency (usually auto-immune destruction of pancreatic cells responsible for making insulin). So taking a drug to make your body more sensitive to something it doesn't have is illogical.

More likely than your doctor committing malpractice is you not knowing what kind of diabetes your father actually has. Or maybe you made a typo. I did that already just writing this. Easy to do.

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TheLiarParadox
02/23/24 2:18:11 PM
#53:


Dark_Arbron posted...
Its a problem that doctors prescribe it to people who dont need it.
Obese people are at a significantly higher risk of developing type 2 diabetes and weight management can be a great way to prevent that. It's not the same as a diabetic person who needs it to live day to day but if we're looking at the broader picture, obese people "need it" too. Time and luck are really the only differences between an obese person using it for weight loss and using it for type 2 diabetes anyway.

The only people who categorically do not need it are non-obese people looking to lose a few vanity pounds.

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