Lurker > Tom_Joad

This is definitely something Japan thought of

Clinical human trials of the intestinal breathing method could start as early as this year.

https://www.vice.com/en/article/epzxj4/pig-breathe-through-anus-study

Pink, fleshy, and round, the anus has a lot in common with the mouth and is every bit as important.

But the similarities dont just stop there. Buttholes can also help animals breathe, new research suggests.

A team of scholars in Japan has found that pigs can absorb oxygen through the anus, in studies exploring treatment for people with respiratory conditions.

By pumping oxygen and oxygenated liquid through animals buttholes into their intestines, the researchers found that they could survive without breathing through their lungs.

It's so impressive because we never thought of breathing from the gut, but its possible, Takanori Takebe, an author of the study and a doctor at the Tokyo Medical and Dental University, told VICE World News.

Last year, his team and collaborators from Nagoya University Graduate School and Kyoto Universitys Department of Respiratory Surgery published their study focusing on mice. Now theyre looking to submit their research on pigs, which are closer to humans in physiology and genetic makeup, to a U.S. medical journal in August.

The scientists were inspired to explore the unconventional breathing method by loaches, a freshwater fish that can use its intestines to breathe. They found that in extensive hypoxic conditionswhen there isnt enough oxygen available at the tissue levelthe structure of loaches gut tissues changed to allow for easier breathing.

In order to see if mammals would also breathe through their anus in oxygen-deprived conditions, Takebe first tested mice. The findings, published in the journal Med last year, were stunning, he said.

Im always very skeptical about the results, but it turns out every time we do the tests, we can get reproducible datasets, said Takebe, who practices medicine also at the Cincinnati Childrens Hospital Medical Center.

The study has implications for treating patients who suffer respiratory failure.

Normally when a patient needs oxygen, doctors opt for mechanical ventilation, in which a machine pushes air into the lungs through the windpipe. They can also use another technique called extracorporeal membrane oxygenation, when blood is pumped out of the body and reoxygenated with a machine.

But this procedure carries the risk of bleeding and blood clots. And as many emergency rooms saw during the early stages of the COVID-19 pandemic, its not always possible to get your hands on a ventilator.

With this in mind, Takebe thought, why not try the backdoor?

To test mammals, Takebe and his co-authors first pumped oxygen gas into the anuses of oxygen-deprived mice. They found that mice that received the treatment lived longer than the ones that didnt.

Then they took the experiment one step further by eliminating barriers that could prevent oxygen uptake in the gut. They scraped the mices mucosa, the innermost layer of the gastrointestinal tract, and injected the gaseous oxygen into the animals.

This helped the rodents survive even longer. Whats more, unlike untreated animals, the mice with their mucosa removed stopped gasping for air altogether and showed no signs of cardiac arrest.

But given mucosal removal might be uncomfortable for patients, the researchers tried a different approachdelivering oxygen in liquid form.

They added oxygen to perfluorodecalin, a chemical that can dissolve large amounts of oxygen. In the past, the substance has been used to treat infants with severe respiratory distress and as artificial blood to improve tissue oxygenation. After shooting the liquid up the mices rectums, the scientists found oxygen levels were further improved. The same was true when they tested pigs and rats.

In a 50-kilogram pig, when we provide this size of liquid oxygen to the butt, they can survive 30 minutes even when experiencing lethal respiratory failure conditions, Takebe said.

Caleb Kelly, a gastroenterology fellow at Yale University whos not affiliated with the study, described the scientists newfound method as promising.

The pandemic has highlighted the need to expand options for ventilation and oxygenation in critical illness, and this niche will persist even as the pandemic subsides, he wrote in a commentary accompanying the 2021 study.

But Kelly noted the animal models dont fully imitate what critically ill patients might experience during respiratory failure, which often coincides with infection, inflammation, and low blood flow. These added factors could complicate the anal ventilation method when tried on humans.
Takebe plans to start human clinical trials as early as this year to prove its real-life efficacy.

Similar to how automated external defibrillatorsportable medical devices used to help those experiencing sudden cardiac arrestare placed throughout public spaces like buildings and schools, Takebe said a shot of liquid oxygen could be made available to save those suffering sudden respiratory failure.

After confirming the safety of this method by testing healthy volunteers in a hospital, Takebe said he planned to recruit patients with respiratory conditions to put his findings to the test.

The user can channel their bio-energy field to draw in ambient energy to infinitely produce solar force from their bodies. They are able to generate from themselves any energies, forces, and substances comprising extraterrestrial suns. The user can then channel and direct them to any kind of purpose. They can even absorb these forces, substances, and related energies into their being.

The user is able to amplify/concentrate the energy they possess, increasing the quantity/amplifying its destructive power.

The user is made up of or can transform their body completely into titanium. A user's transformed form is anatomically identical to their normal form, aside of being made of titanium, in which case it contains all to organs and is somewhat vulnerable to attacks. Alternately the user can transform into homogeneous matter, without any part of their form being more important than the other.

The user, either innately or through training, is a master of safecracking, able to open any safe no matter the complexity of the code.

The Lost Balls
Frankenball
Re-Animballator
Night of the Living Balls

I turn into a tardigrade to withstand the heat of their chi and enter their body, then turn into an elephant and explode them. Shooting fluid out my eyes is a declaration of victory. This is assuming that I'm not incinerated by an unfeeling fireblast first.

Don't a lot of people give up eating meat because of all the factory farming cruelty involved or the absurd amount of resources needed to produce meat compared to veggies? Not necessarily because they dislike eating meat.

How does it feel to be the villain of a PS1 platformer?

So you're basically a god and you're fucking with a weird little salamander dude.

The power to have the traits and powers of mythological beings from Portuguese Folklore/Legends.

Beings from Portuguese legends can range from Ghosts, historical figures that gain almost divine status or even Titans such as the Adamastor. These legends are often metaphors for the fears of traveling through the sea or depict people who are rewarded for their actions.

The user can condemn beings/souls to hell where they will suffer constant torment and torture from beings in hell. This can cause insanity and a loss of one's self.

The user either is or can mimic/transform into a caudata, members of the salamander clade. It list urodela (salamanders) and extinct salamander-like species.

The user can perform totally random and unpredictable forms of combat that are either to mock their enemies or just for the fun of it, using various unorthodox tactics so the opponent never knows what to expect.

Cthulhu kills all of them, even though he's dead.

when i rented a car a couple months ago to go down to San Diego for my grandfather's memorial service, it didn't even have a shifter knob at all, it was all individual buttons on the center console. it was weird. i don't see why they have to go and change shit in cars that didn't need to be changed. why can't they just make them like they've always made them.

Alternative seafood is having a moment, with the rise of companies like BlueNalu and Wildtype, which has the backing of Leonardo DiCaprio

https://www.theguardian.com/environment/2022/oct/22/lab-grown-fish-cell-seafood-bluenalu-wildtype

In the middle of San Francisco, theres a pilot production plant for Wildtype, one of a handful of cell-cultivated seafood companies in the US. Inside, its growing sushi-grade coho salmon in tanks similar to those found in breweries no fishing or farming required.

Cultivation starts by taking a small sample from a living fish species. Cells then multiply as they would in nature in the large vessels and eventually become fatty and lean parts of a fish fillet.

Depending on whom you talk to, fishless fish could be the next big thing in seafood production. While plant-based seafood products in the US account for only 0.1% of seafood sales less than the 1.4% of the US meat market is occupied by plant-based meat alternatives venture capitalists are getting serious about cell-based seafood. San Diego-based BlueNalu has raised $84.6m (74.8m) since its founding in 2018, and Wildtype has received $100m (88.4m) in series B funding with investments from Leonardo DiCaprio, Bezos Expeditions and Robert Downey Jrs FootPrint Coalition, among others.

Entrepreneurs and advocates say cruelty-free cell-cultivated seafood is a solution to the seafood industrys many environmental problems, including overfishing, health risks from mercury and microplastics, and lack of traceability. The current unsustainable seafood supply chain typically has up to 10 to 15 intermediaries between fishers or farmers and the person who ultimately purchases it.

Wildtypes co-founder and CEO, Justin Kolbeck, a former diplomat who has worked on food insecurity abroad, worries about how current practices would feed a growing populations demand for seafood.

The scope of what were facing is so massive that if we dont all succeed, we as a species will collectively fail, he said. We cant fix this when were at that point we need to fix it now when theres still time for oceans to recover.

In many cases, seafood products travel multiple times around the world before reaching the end consumer.

Were one environmental disaster away from extraordinary disruption to the supply chain and the global consumption of seafood is at an all-time high, said Lou Cooperhouse, founder and CEO of BlueNalu, which is initially focused on growing bluefin tuna toro. In the next decade, he envisions factories being built around the world that can meet consumption demands and says they are ready to scale quickly.

Sustainable sources of seafood are needed to meet the demand from a growing global population that is on pace to reach 10 billion by 2050. While plant-based alternatives that look and taste like fish are gaining traction, cruelty-free cultivated seafood products could be on dinner plates in the next year or two, pending regulatory approval from the US food and drug administration.

But critics say in order for cell-cultivated seafood to be a better bet for the planet than fishing or farming, the industry would have to make their expensive products cost-competitive and get consumers to willingly substitute it for wild-caught fish.

It also needs to be eaten in numbers high enough to replace wild-caught fish. Researchers say this is unlikely, given the fact that aquaculture, the farming of aquatic organisms, hasnt succeeded in replacing global wild-caught fisheries but is simply adding to seafood production.

Im really skeptical of claims that cell-based seafood companies will make a difference for fisheries and ocean conservation, said Benjamin Halpern, a marine biologist at the University of California, Santa Barbara, who has researched cultivated seafoods ability to reduce fishing pressure.

The state of California recently made the largest single investment in alternative protein research of any US state. The $5m (4.4m) in funding is being split between three University of California schools: UC Berkeley, UC Davis and UCLA. And the Biden administration is backing lab-grown meat as referenced in a recent executive order.

When grown indoors, cell-cultured seafood like salmon and tuna can be optimized for taste, texture and nutritional content, and cooked like traditional fish or eaten like sushi. But it remains unknown if consumers will embrace lab-grown fish.

We talk a lot about price, taste and convenience as the three core aspects the alt-protein industry needs to focus on, said Marika Azoff, a corporate engagement specialist at the Good Food Institute, a non-profit advocacy group that promotes alternative proteins. They need to taste the same or better, they need to be priced the same or cheaper, and they need to be widely available.

Even cell-cultivated skeptics agree that hi-tech seafood has a huge market potential, but they say its going to always be an expensive product even though costs are coming down with time. They also note that species such as salmon and tuna arent particularly threatened worldwide.

This is feeding the affluent another food product, said UCSBs Halpern. Even at the cheapest level and it will never be that cheap its not going to be the food product most people eat around the world.

BlueNalu recently announced that it cracked the code to significant profitability in its first large-scale facility, thanks in part to technologies that reduce operating and capital costs. When combined with the companys high-end product and market focus, the company says they will enable a projected 75% gross margin.

I see a role for alternative seafood production in the sustainable seafood equation, just as I do for sustainably harvested wild fisheries and sustainable aquaculture, said Rob Jones, global head of aquaculture at the Nature Conservancy. Both cell-based and plant-based seafood can be a part of that future.

Jones said alternative seafood products could achieve a similar 1% to 2% of the overall market, similar to plant-based meats, but that the full environmental and social effects of the production methods, such as carbon emissions and ingredient sourcing policies, must be considered.

Most alt-seafood companies wont share their intellectual property and its unknown just how energy-intensive cell culturing is at this stage. BlueNalus Cooperhouse likens it to beer or beverage production and says its important to remember that the current seafood industry is incredibly resource-intensive.

Your resources are labor on ships, oil, massive transportation and the many animal lives lost for a very inefficient 50% to 70% yield depending on species, he said. Lets address the global supply chain issues and solve them one species at a time.

BlueNalu and Wildtype say theres no single solution to meeting the worlds demand for seafood, but believe their presence can lead to greater sustainability in the industry.

Fish farms recognize that their current practices need to change and commercial fishing operations know something needs to change, said Wildtypes co-founder Ary Elfenbein, who is also a cardiologist. Our role is to assist with that transition thats really what were there for.

i have to say no. i hate runny eggs

*grabs flame shield.

Do non Floridians all suddenly melt to death if da temp gets over 70?

I picked complain about something I like. I have a coworker that absolutely detests anime. Every now and then I like to wind her up and just let her go off, it's genuinely amusing.

One day she was being particularly cantankerous so I decided to put on some Japanese pop/rock just to really get under her skin.

that's not bad actually. I rate it a 4/10

https://gamefaqs.gamespot.com/a/user_image/0/6/0/AABhrNAADyck.jpg

How the FUCK can you HATE black eyed PEAS

Yep

My Opposite Sex Clone Works For The NSA, While Ojou-sama Is Addicted To Eroge!