Urameshi and his two demon buddies were pushing DBZ levels at the end. Speed so fast you can't see them, punches so hard it shatters mountains, and so on. I'm pretty sure he's also tanked his own shot before, or at least blasts comparable.
Yusuke is a stamina machine, no one can keep going as long as he can. How long can Minato teleport without losing energy?
And he uses both kinds of energy. If he happens to get sealed while in close combat he'd just use it to his advantage and surprise him with his alternate source attack.