Homura's normal opener is to pause time, fire a lot of bullets at the enemy (which remain frozen in air), then unpause time, at which point all the bullets become unfrozen and strike the target simultaneously. I don't see Red surviving that.
Also, this would occur quickly enough (from the perspective of anyone not Homura) that I wouldn't see his pokemon being able to intercept the bullets to save him, even assuming that he would be able to send one out before her initial time freeze.
Homura.
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another place and time, without a great divide, and we could be flying deadly high