LogFAQs > #968946021

Brick pops back up if you save him but it's a side quest from a character you don't get introduced to until way later in the game, so much later that I wouldn't be surprised if most people made it to the point of no return and never got to that string of characters. Also it's not a remarkable cameo, saving Brick makes the future gig so much easier and makes a unique weapon missable.